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CHRM1 pAb

CHRM1 pAb

Cat no: BS6565


Supplier: Bioworld Technology, Inc.
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The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, brea own of phosphoinositides and modulation of potassium channels. The mAChRs transduce signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.
Catalogue number: BS6565
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P11229
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human CHRM1.
Species: CHRM1 pAb detects endogenous levels of CHRM1 protein.
Molecular weight: ~ 51 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Cholinergic receptor muscarinic 1; CHRM 1; CHRM1; HM 1; HM1; M1; M1 muscarinic cholinergic receptor; MGC30125; Muscarinic acetylcholine receptor M1;
Additional info: For research use only, not for use in diagnostic procedure.

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