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Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI)

Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI)

Cat no: C5069-97F

Supplier: United States Biological
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Chromogranin A is a protein of 439aa which is encoded on chromosome 14. It is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Applications: Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:400 for 10 mins. at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions to be determined by the researcher. Cellular Localization: Cytoplasmic Positive Control: Pancreas Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C5069-97F
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 1ml
Form: Supplied as a liquid in PBS, pH 7.4, containing sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography
Alternative names: CGA, CHG A, Chromogranin A parathyroid secretory protein 1, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI
Additional info: Recognizes human Chromogranin A

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