Chromogranin A (CGA, CHG A, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI)

Chromogranin A is a protein of 439aa which is encoded on chromosome 14. It is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.\n\nApplications: \nSuitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (paraffin): 1:400 for 10 mins. at RT. Staining of formalin-fixed tissues \nrequires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by \ncooling at RT for 20 min.\nOptimal dilutions to be determined by the researcher.\n\nCellular Localization: Cytoplasmic\n\nPositive Control: Pancreas\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C5069-97F

Size

1ml

Applications

IHC

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, containing sodium azide\n

P Type

Pab

Purity

Purified by immunoaffinity chromatography

Isotype

IgG

Additional Info

Recognizes human Chromogranin A

Alternative Names

CGA, CHG A, Chromogranin A parathyroid secretory protein 1, Pancreastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Vasostatin, SPI