CIITA (Class II Trans Activator, C2TA, CIITA IV, MHC2TA, MHC Class II Transactivator)

Cat no: C5072-61B

Supplier: United States Biological

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CIITA is a non-DNA binding coactivator considered as the master regulator of basal and induced MHC class II specific gene expression. CIITA ensures a tight transcriptional control of these antigen-presenting genes to meet with local requirements for an adequate immune response. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C5072-61B
Reactivities:	Human
Hosts:	Mouse
Applications:	ELISA, Immunoprecipitation, Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein G affinity chromatography.
References:	1. LeibundGut-Landmann, S., et al., Eur. J. Immunol. 34: 1513-1525 (2004). 2. Van den Elsen, P., et al., Curr. Opin. Immunol. 16: 67-75 (2004). 3. Naves, R., et al., Int. Immunol. 14: 481-491 (2002).
Additional info:	Recognizes human CIITA.

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CIITA (Class II Trans Activator, C2TA, CIITA IV, MHC2TA, MHC Class II Transactivator)

Cat no: C5072-61B

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