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CIITA (T740) Peptide

CIITA (T740) Peptide

Cat no: BS2471P


Supplier: Bioworld Technology, Inc.
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The transactivator CIITA regulates basal and interferon-induced expression of MHC class II genes. CIITA restores expression of all MHC II gene expression in mutant cells and corrects regulatory defects of those genes. Activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. CIITA may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter.
Catalogue number: BS2471P
Applications: Block/Neutralize/Inhibit
Swiss prot: P33076
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CIITA (T740). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MHC class II transactivator; CIITA; C2TA; MHC2TA
Additional info: This peptide can be used with studies using BS2471 CIITA (T740) pAb.

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