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CIITA (T740) Peptide

Cat no: BS2471P

CIITA (T740) Peptide

The transactivator CIITA regulates basal and interferon-induced expression of MHC class II genes. CIITA restores expression of all MHC II gene expression in mutant cells and corrects regulatory defects of those genes. Activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. CIITA may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter.

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SPECIFICATIONS

Catalog Number

BS2471P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide CIITA (T740). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P33076

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2471 CIITA (T740) pAb.

Alternative Names

MHC class II transactivator; CIITA; C2TA; MHC2TA

SUPPLIER INFO

Bioworld Technology, Inc.

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