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Claudin-1 (R197) Peptide

Claudin-1 (R197) Peptide

Cat no: BS1063P


Supplier: Bioworld Technology, Inc.
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The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Catalogue number: BS1063P
Applications: Block/Neutralize/Inhibit
Swiss prot: O95832
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Claudin-1 (R197). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Claudin1; CLD1; ILVASC; SEMP1; Claudin 1; CLDN1; UNQ481/PRO944
Additional info: This peptide can be used with studies using BS1063 Claudin-1 (R197) pAb.

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