Home  >  Products  >  Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8)
Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8)

Claudin 4 (Claudin-4, CLDN4, Clostridium perfringens Enterotoxin Receptor, CPE-receptor, CPER, CPE-R, hCPE-R, CPETR, CPETR1, Williams-Beuren Syndrome Chromosomal Region 8 Protein, WBSCR8)

Cat no: C5838-37

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Claudin-4 is a member of the claudin family and one of the integral constituents of tight junctions. Tight junctions are the most apical component of intercellular junctional complexes, thereby establishing cell polarity and functioning as major determinants of paracellular permeability. Claudin-4 is overexpressed in the majority of pancreatic carcinomas and functions as a receptor for cytotoxic CPE. It consists of 209 amino acids and contains four putative transmembrane segments. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:100-1:200 Optimal dilutions to be determined by the researcher. Positive Control: Ovarian carcinoma, tonsil Cellular Localization: Cytoplasmic and cell membrane Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C5838-37
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 500ul
Form: Supplied as a liquid in 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Patrick et al. Cancer Research 63: 6265, 2003.
Additional info: Recognizes human Claudin 4. Species Crossreactivity: mouse.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave