CLC-6 (K649) Peptide

Cat no: BS3104P

Supplier: Bioworld Technology, Inc.

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The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7, 3q26, 4q32, Xp22, Xp11, 1p36 and 16p13, respectively. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. CLC-3 expression is particularly abundant in neuronal tissue, while CLC-4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC-5 lead to Dent

Catalogue number:	BS3104P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P51797
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CLC-6 (K649). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	CLCN6; CLC-6; KIAA0046
Additional info:	This peptide can be used with studies using BS3104 CLC-6 (K649) pAb.

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CLC-6 (K649) Peptide

Cat no: BS3104P

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