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CLCNKA Peptide

CLCNKA Peptide

Cat no: BS5665P

Supplier: Bioworld Technology, Inc.
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CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter
Catalogue number: BS5665P
Applications: Block/Neutralize/Inhibit
Swiss prot: P51800
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CLCNKA. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1; CLC-KA; CLCKA
Additional info: This peptide can be used with studies using BS5665 CLCNKA pAb.

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