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Clostridium botulinum Toxin A (BoNT/A, Bontoxilysin-A)

Cat no: C5851-80J


Supplier: United States Biological
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Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln--Arg-198 bond of SNAP-25. Applications: Suitable for use in ELISA, Dot Blot and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C5851-80J
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.2, 20% glycerol. No preservatives added.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes Clostridium botulinum Type A Neurotoxin Light Chain.

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