Connexin 26 (H94) pAb

Cat no: BS3443

Supplier: Bioworld Technology, Inc.

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Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, approximately half the cases of autosomal recessive non-syndromic hearing loss and a significant proportion of sporadic hearing loss can be linked to mutation in the gene encoding connexin 26.

Catalogue number:	BS3443
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	P29033
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 60-110 of Human Connexin 26.
Species:	Connexin-26 (H94) pAb detects endogenous levels of Connexin-26 protein.
Molecular weight:	~ 28 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Gap junction beta-2 protein; Connexin-26; Cx26; GJB2
Additional info:	For research use only, not for use in diagnostic procedure.

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Connexin 26 (H94) pAb

Cat no: BS3443

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