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Connexin 32 (L115) pAb

Cat no: BS3527

Connexin 32 (L115) pAb

Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, mutations in connexin 32 result in Charcot-Marie-Tooth disease, a demyelinating disease of the peripheral nervous system.

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SPECIFICATIONS

Catalog Number

BS3527

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 81-130 of Human Connexin 32.

Species

Connexin-32 (L115) pAb detects endogenous levels of Connexin-32 protein.

Dilutions

WB: 1:500~1:1000\nIHC: 1:50~1:200

Swiss Prot

P08034

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 32 kDa

Alternative Names

Gap junction beta-1 protein; Connexin-32; Cx32; GAP junction 28 kDa liver protein; CX32; GJB1

SUPPLIER INFO

Bioworld Technology, Inc.

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