Connexin 32 (L115) pAb

Cat no: BS3527

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, mutations in connexin 32 result in Charcot-Marie-Tooth disease, a demyelinating disease of the peripheral nervous system.

Catalogue number:	BS3527
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P08034
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 81-130 of Human Connexin 32.
Species:	Connexin-32 (L115) pAb detects endogenous levels of Connexin-32 protein.
Molecular weight:	~ 32 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Gap junction beta-1 protein; Connexin-32; Cx32; GAP junction 28 kDa liver protein; CX32; GJB1
Additional info:	For research use only, not for use in diagnostic procedure.

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Connexin 32 (L115) pAb

Cat no: BS3527

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