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Connexin 43 (S369) Peptide

Connexin 43 (S369) Peptide

Cat no: BS1073P

Supplier: Bioworld Technology, Inc.
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Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions. Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication. Src can interact with and phosphorylate Cx43 to alter gap junction communication.
Catalogue number: BS1073P
Applications: Block/Neutralize/Inhibit
Swiss prot: P17302
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Connexin 43 (S369). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Gap junction alpha-1 protein; Connexin-43; Connexin 43; Connexin43; Cx43; Cx-43; Gap junction 43 kDa heart protein; GJA1; GJAL
Additional info: This peptide can be used with studies using BS1073 Connexin 43 (S369) pAb.

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