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COPS5 / JAB1 (K191) Peptide

COPS5 / JAB1 (K191) Peptide

Cat no: BS2340P

Supplier: Bioworld Technology, Inc.
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Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, but the Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. The coactivator of Jun, designated JAB1 (for Junactivation
Catalogue number: BS2340P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q92905
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide COPS5 / JAB1 (K191). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: COP9 signalosome complex subunit 5; SGN5; Signalosome subunit 5; Jun activation domain-binding protein; COPS5; CSN5; JAB1
Additional info: This peptide can be used with studies using BS2340 COPS5 / JAB1 (K191) pAb.

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