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CREM (I106) Peptide

CREM (I106) Peptide

Cat no: BS2032P

Supplier: Bioworld Technology, Inc.
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The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The ATF/CREB family includes CREM, CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. The transcription factor cAMP-responsive element modulator (CREM) is known to play a vital role for male fertility as it has been demonstrated that male mice lacking a functional CREM gene are infertile. In testis, CREM transcriptional activity is controlled through interaction with a tissue-specific partner, activator of CREM in the testis (ACT), which confers a powerful, phosphorylation-independent activation capacity.
Catalogue number: BS2032P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q03060
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CREM (I106). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: cAMP-responsive element modulator; Inducible cAMP early repressor; ICER; CREM
Additional info: This peptide can be used with studies using BS2032 CREM (I106) pAb.

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