CRP Peptide

Cat no: BS60395P

Supplier: Bioworld Technology, Inc.

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Pentraxins, which include C-reactive protein (CRP) and serum amyloid P component (SAP), are prototypic acute phase proteins. CRP and SAP are produced by liver epithelial cells and are characterized by a cyclic pentameric structure and calcium-dependent ligand binding. IL-6 is the major inducer of human CRP gene, and IL-1 and steroids can enhance this induction. Testosterone is required for the expression of CRP transgene in vivo, whereas testosterone is not required for expression of the SAP gene. During the acute-phase response, cytokine C5a acts with IL-6 and/or IL-1b to promote upregulation of the CRP and SAP genes. Both Stat3 and C/EBP are involved in mouse SAP gene expression, but only Stat3 is involved in mouse CRP gene expression. SAP binds to a variety of molecules, including autoantigens and chromatin.

Catalogue number:	BS60395P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P02741
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CRP. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	C reactive protein; C reactive protein pentraxin related; C-reactive protein(1-205); CRP; CRP; CRP; MGC88244; Pentraxin 1; PTX 1; PTX1;
Additional info:	This peptide can be used with studies using BS60395 CRP pAb.

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CRP Peptide

Cat no: BS60395P

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