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CSF2RA pAb

CSF2RA pAb

Cat no: BS6570

Supplier: Bioworld Technology, Inc.
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The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common (beta) subunit. The a subunits are low affinity ligand binding proteins while the (beta) subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct (beta) subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine (beta)-subunits are 91% homologous at the amino acid level but only 56% homologous to the human (beta) subunit. Although neither the murine nor the human (beta) subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Catalogue number: BS6570
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P15509
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human CSF2RA.
Species: CSF2RA pAb detects endogenous levels of CSF2RA protein.
Molecular weight: ~ 46 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CD116; CD116 antigen; CDw116; Colony stimulating factor 2 receptor alpha chain; CSF 2R; CSF2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM CSF R alpha; GM CSF receptor alpha subunit; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR-alpha; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha;
Additional info: For research use only, not for use in diagnostic procedure.

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