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CstF-64 (R46) Peptide

CstF-64 (R46) Peptide

Cat no: BS1980P

Supplier: Bioworld Technology, Inc.
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CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF. CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, but not meiotic, germ cells. However, a large variant of CstF-64, called t CstF-64, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, and promotes the germ cell pattern of polyadenylation. The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, whereas t CstF-64 is encoded by an autosomal gene. The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation.
Catalogue number: BS1980P
Applications: Block/Neutralize/Inhibit
Swiss prot: P33240
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CstF-64 (R46). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cleavage stimulation factor 64 kDa subunit; CSTF 64 kDa subunit; CF-1 64 kDa subunit; CstF64; CstF 64; CSTF2;
Additional info: This peptide can be used with studies using BS1980 CstF-64 (R46) pAb.

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