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CtBP2 (P432) Peptide

CtBP2 (P432) Peptide

Cat no: BS2287P


Supplier: Bioworld Technology, Inc.
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CtBP1 and the related protein CtBP2 are characterized as C-terminal binding proteins of adenovirus E1A, and they preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation.CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of deltaEF1, a cellular zinc finger-homeodomainprotein, and thereby enhances deltaEF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity.
Catalogue number: BS2287P
Applications: Block/Neutralize/Inhibit
Swiss prot: P56545
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CtBP2 (P432). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: C-terminal-binding protein 2; CtBP2; CTBP2
Additional info: This peptide can be used with studies using BS2287 CtBP2 (P432) pAb.

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