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CUL-1 (Y761) Peptide

CUL-1 (Y761) Peptide

Cat no: BS1081P

Supplier: Bioworld Technology, Inc.
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CUL-1, which is the mammalian homolog of yeast Cdc53, is an integral component of the E3 ubiquitin ligase complex designated SCF. The SCF (Skp1/CUL-1/F-box protein complex) consists of Skp1 associating with both CUL-1 and an F-box protein, such as Skp2, which determines the substrate specificity of the complex. CUL-1-mediated ubiquitination results in the degradation of cell cycle proteins cyclin D, p21 and cyclin E. Another cullin, CUL-3, facilitates the degradation of cyclin E independent of SCF activity, while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes, which structurally resemble the SCF ligase.
Catalogue number: BS1081P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13616
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CUL-1 (Y761). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: CUL 1; CUL-1; CUL1; CUL1; Cullin-1; Cullin1; MGC149834; MGC149835;
Additional info: This peptide can be used with studies using BS1081 CUL-1 (Y761) pAb.

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