CXCL10 pAb

Chemokines are members of a superfamily of inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20% to 50% homology in their predicted amino acid sequences and are divided into four subfamilies: C-C, C-X-C, C and C-X3-C. In the C-X-C or (alpha) subfamily, the first two of four cysteine motifs are separated by another amino acid residue. In the second subfamily, designated C-C or (beta), the first cysteines are adjacent. C subfamily members, also designated (gamma) chemokines, lack the first and third cysteine residues of the conserved motif. In the C-X3-C, or (delta) subfamily, members have three amino acids between the two cysteines. The C-X-C chemokine subfamily includes IL-8, GRO(alpha)/(beta)/(gamma) (and the murine homologs KC, MIP-2(alpha) and MIP-2(beta)), platelet basic protein, ENA-78, GCP-2, PF4, IP-10 (and its murine homolog, CRG) and MIG.

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SPECIFICATIONS

Catalog Number

BS6828

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human CXCL10.

Species

CXCL10 pAb detects endogenous levels of CXCL10 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P02778

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul