Cyclin G (I194)Peptide

Cat no: BS1088P

Supplier: Bioworld Technology, Inc.

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Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.

Catalogue number:	BS1088P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P51959
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Cyclin G (I194). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Cyclin-G1; Cyclin-G; CCNG1; CCNG; CYCG1
Additional info:	This peptide can be used with studies using BS1088 Cyclin G (I194)pAb.

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Cyclin G (I194)Peptide

Cat no: BS1088P

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