Cyclin H mAb

Cat no: MB0018

Supplier: Bioworld Technology, Inc.

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Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Catalogue number:	MB0018
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunoprecipitation, Western Blot
Size:	100ug/100ul
Swiss prot:	P51946
Dilutions:	WB: 1:1000 IP: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human Cyclin H.
Species:	This antibody detects endogenous levels of CCNH and does not cross-react with related proteins
Molecular weight:	Predicted band size:38KDa Observed band size:38KDa
Purity:	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	MO15-associated protein; p34; p37; CCNH
Additional info:	For research use only, not for use in diagnostic procedure.

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Cyclin H mAb

Cat no: MB0018

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