CYP21A2 (F177) Peptide

Cat no: BS2189P

Supplier: Bioworld Technology, Inc.

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The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP21A2 localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Activity of CYP21A2 is required for the synthesis of steroid hormones, including cortisol and aldosterone. Mutations in this gene is the primary cause of congenital adrenal hyperplasia (CAH), an autosomal recessive disorder. Gene conversion events involving the functional CYP21A2 gene (C21B) and a related pseudogene (C21A) located near the C21B gene may account for the majority of cases of steroid 21-hydroxylase deficiency.

Catalogue number:	BS2189P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P08686
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide CYP21A2 (F177). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Steroid 21-hydroxylase; 21-OHase; Cytochrome P-450c21; Cytochrome P450 21; Cytochrome P450 XXI; Cytochrome P450-C21; Cytochrome P450-C21B; CYP21A2; CYP21; CYP21B
Additional info:	This peptide can be used with studies using BS2189 CYP21A2 (F177) pAb.

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CYP21A2 (F177) Peptide

Cat no: BS2189P

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