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CYP2D6 (A277) Peptide

CYP2D6 (A277) Peptide

Cat no: BS2681P

Supplier: Bioworld Technology, Inc.
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Enhanced CYP2D6 activity has been related to malignancies of the bladder, liver, pharynx, and stomach and, especially, to cigarette-smoking-induced lung cancer. The data suggests that enhanced CYP2D6-mediated metabolism of one or more dietary and other environmental agents, to form a reactive intermediate, plays a role in cancer initiation and/or promotion in various tissues. CYP2D6 polymorphism, which is responsible for the variation in metabolism of debrisoquine 4-hydroxylase, is important in the metabolism of more than 30 drugs and environmental chemicals, including as much as 20% of all commonly prescribed drugs.
Catalogue number: BS2681P
Applications: Block/Neutralize/Inhibit
Swiss prot: P10635
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CYP2D6 (A277). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cytochrome P450 2D6; CYPIID6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase; CYP2DL1
Additional info: This peptide can be used with studies using BS2681 CYP2D6 (A277) pAb.

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