Cystatin C (F122) Peptide

Cat no: BS3973P

Supplier: Bioworld Technology, Inc.

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Additional Information

Cystatin C is a cysteine (thiol) protease inhibitor that belongs to the type II cystatin gene superfamily and is the most abundant extracellular inhibitor of cysteine proteases. Cystatin C is a constitutively secreted, amyloidogenic protein, which forms a two-fold symmetric dimer and modulates both cysteine protease activity and the expression of class II MHC molecules. Expression of cystatin C is an indicator of kidney function and glomerular filtration rate. Mutations in the cystatin C gene can lead to protein aggregates, which are implicated in hereditary amyloid angiopathy (HCCAA) and cerebral hemorrhage. Although both wild-type and mutant cystatin C are capable of forming concentration dependent inactive dimers, mutant cystatin C dimerizes at lower concentrations and is more susceptible to serine proteases, which may facilitate aggregation. In neuronal cells, oxidative stress stimulates expression of cystatin C, which may positively regulate apoptosis.

Catalogue number:	BS3973P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P01034
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Cystatin C (F122). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ARMD11; MGC117328;CST3;
Additional info:	This peptide can be used with studies using BS3973 Cystatin C (F122) pAb.

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Cystatin C (F122) Peptide

Cat no: BS3973P

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