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Cytochrome c1 (M166) Peptide

Cytochrome c1 (M166) Peptide

Cat no: BS9260P

Supplier: Bioworld Technology, Inc.
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Cytochrome c is a well characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial intermembrane space. More recent studies have identifed cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is translocated from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
Catalogue number: BS9260P
Applications: Block/Neutralize/Inhibit
Swiss prot: P99999
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Cytochrome c1 (M166). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Complex III subunit 4; Complex III subunit IV; CY1; CYC1; Cytochrome b c1 complex subunit 4; Cytochrome b-c1 complex subunit 4; Cytochrome bc1 complex subunit 4; Cytochrome c 1; Cytochrome c-1; Cytochrome c1; heme protein; mitochondrial; Ubiquinol cytochrome c reductase complex cytochrome c1 subunit; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; UQCR4;
Additional info: This peptide can be used with studies using BS9260 Cytochrome c1 (M166) pAb.

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