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Cytokeratin 10 (Y160) pAb

Cytokeratin 10 (Y160) pAb

Cat no: BS1199


Supplier: Bioworld Technology, Inc.
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Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.
Catalogue number: BS1199
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P13645
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 130-180 of Human Cytokeratin 10.
Species: Cytokeratin 10 (Y160) pAb detects endogenous levels of Cytokeratin 10 protein.
Molecular weight: ~ 59 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Keratin, type I cytoskeletal 10; Cytokeratin-10; Short name=CK-10; Keratin-10; Short name=K10; KRT10; KPP; CK-10; CK 10; CK10; Keratin 10; Keratin10
Additional info: For research use only, not for use in diagnostic procedure.

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