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Cytokeratin 16 (S451) Peptide

Cytokeratin 16 (S451) Peptide

Cat no: BS1202P

Supplier: Bioworld Technology, Inc.
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Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating
Catalogue number: BS1202P
Applications: Block/Neutralize/Inhibit
Swiss prot: P08779
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Cytokeratin 16 (S451). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Keratin, type I cytoskeletal 16; Cytokeratin-16; Cytokeratin16; CK-16; CK16; Keratin-16; Keratin 16; Keratin16; Short name=K16; KRT16; KRT16A
Additional info: This peptide can be used with studies using BS1202 Cytokeratin 16 (S451) pAb.

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