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Cytokeratin 19 (L349) pAb

Cytokeratin 19 (L349) pAb

Cat no: BS3540

Supplier: Bioworld Technology, Inc.
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This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
Catalogue number: BS3540
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P08727
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 321-370 of Human Cytokeratin 19.
Species: Cytokeratin
Molecular weight: ~ 44 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CK 19; CK-19; ck19; Cytokeratin 19; Cytokeratin-19; k19; K1C19; k1cs; Keratin 19; Keratin type I 40; Keratin type i 40; Keratin type I cytoskeletal 19; Keratin; type I cytoskeletal 19; Keratin; type I; 40; Keratin-19; krt19
Additional info: For research use only, not for use in diagnostic procedure.

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