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Cytokeratin 5 (S573) pAb

Cytokeratin 5 (S573) pAb

Cat no: BS1208


Supplier: Bioworld Technology, Inc.
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Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
Catalogue number: BS1208
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P13647
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 550-600 of Human Cytokeratin 5.
Species: Cytokeratin 5 (S573) pAb detects endogenous levels of Cytokeratin 5 protein.
Molecular weight: ~ 62 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; Cytokeratin5; Short name=CK-5; CK5; Keratin-5; Keratin5; Keratin 5; Short name=K5; Type-II keratin Kb5; KRT5
Additional info: For research use only, not for use in diagnostic procedure.

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