Home  >  Products  >  Daxx (BING2, DAP 6, DAP6, Death Associated Protein 6, EAP 1, EAP1, ETS1 Associated Protein 1, Fas Death Domain Associated Protein, hDaxx, MGC126245, MGC126246)
Daxx (BING2, DAP 6, DAP6, Death Associated Protein 6, EAP 1, EAP1, ETS1 Associated Protein 1, Fas Death Domain Associated Protein, hDaxx, MGC126245, MGC126246)

Daxx (BING2, DAP 6, DAP6, Death Associated Protein 6, EAP 1, EAP1, ETS1 Associated Protein 1, Fas Death Domain Associated Protein, hDaxx, MGC126245, MGC126246)

Cat no: D1150-01D

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. DAXX is predominantly a nuclear protein, where it acts as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm. Applications: Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 2.5ug/ml ELISA: 1:7000-1:45,000 Western Blot: 1:200-1:1000 Optimal dilutions to be determined by the researcher. Positive Control: human kidney Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D1150-01D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Death Domain-Associated Protein 6. Species Crossreactivity: mouse, rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave