Dbf4 (I18) Peptide

Cat no: BS2372P

Supplier: Bioworld Technology, Inc.

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The Dbf4/Cdc7 protein kinase is essential for the activation of replication origins during S phase. Cdc7-Dbf4 efficiently phosphorylates several proteins that are required for the initiation of DNA replication, including five of the six minichromosome maintenance (Mcm) proteins and the p180 subunit of DNA polymerase alpha-primase. This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4, and the kinase activity of the complex is regulated throughout the cell cycle mainly by fluctuating levels of Dbf4. Cdc7 is consistently expressed throughout the cell cycle, while the expression of Dbf4 is absent during G1 phase and accumulates during S and G2 phases. The anaphase-promoting complex rapidly degrades Dbf4 at the time of chromosome segregation, and the stability of Dbf4 remains low during pre-Start G1 phase.

Catalogue number:	BS2372P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9UBU7
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Dbf4 (I18). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Protein DBF4 homolog A; Activator of S phase kinase; Chiffon homolog A; DBF4-type zinc finger-containing protein 1; DBF4; ASK; DBF4A; ZDBF1
Additional info:	This peptide can be used with studies using BS2372 Dbf4 (I18) pAb.

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Dbf4 (I18) Peptide

Cat no: BS2372P

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