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DCC (F465) Peptide

DCC (F465) Peptide

Cat no: BS3232P

Supplier: Bioworld Technology, Inc.
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DCC (deleted in colorectal cancer) was first identified as a candidate tumor suppressor gene based on its absence or reduced expression in the majority of colorectal cancers. Loss of DCC expression was subsequently observed in cancers of the breast, endometrium, brain, pancreas and prostate, as well as in leukemias, neuroblastomas and male germ cell cancers. DCC is a 1447 amino acid transmembrane protein with highest expression in developing brain and neural tube and is suspected to play a role in mediating directional migration in the developing nervous system. Netrin-1, a chemoattractant for commissural axons in the spinal cord, has been identified as a ligand for DCC.
Catalogue number: BS3232P
Applications: Block/Neutralize/Inhibit
Swiss prot: P43146
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide DCC (F465) . (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Netrin receptor DCC,Colorectal cancer suppressor,Immunoglobulin superfamily DCC subclass member 1,Tumor suppressor protein DCC,IGDCC1,DCC
Additional info: This peptide can be used with studies using BS3232 DCC (F465) pAb .

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