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DCK pAb

DCK pAb

Cat no: BS6581


Supplier: Bioworld Technology, Inc.
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The dCK/dGK family of proteins includes 4 different deoxyribonucleoside kinases including the cytoplasmic (TK1) and mitochondrial (TK2) thymidine kinases, and the deoxycytidine (dCK) and deoxyguanosine (dGK) kinases. Deoxyribonucleoside kinases catalyze the 5'-phosphorylation of 2'-deoxyribonucleosides with nucleoside triphosphates (NTPs) as phosphate donors. The dCK enzyme is associated with drug resistance and sensitivity, as both dCK and TK2 phosphorylate several antiviral and chemotherapeutic nucleoside analogs. Deficiency of dCK activity corresponds with resistance to antiviral and chemotherapeutic agents. dCK and TK1 localize to the cytosol, whereas dCK and TK2 localize to the mitochondria. These deoxyribonucleoside kinases are most abundantly expressed in muscle, brain and liver.
Catalogue number: BS6581
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P27707
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human DCK.
Species: DCK pAb detects endogenous levels of DCK protein.
Molecular weight: ~ 31 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: DCK; DCK protein; DCK; Deoxycytidine kinase; EC 2.7.1; EC 2.7.1.74; MGC117410; MGC138632; OTTHUMP00000219118; OTTHUMP00000219119;
Additional info: For research use only, not for use in diagnostic procedure.

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