Home  >  Products  >  DCP1A (Decapping Enzyme, HSA275986, Nbla00360, SMAD4IP1, SMIF, Smad4-interacting Transcriptional Co-activator)

DCP1A (Decapping Enzyme, HSA275986, Nbla00360, SMAD4IP1, SMIF, Smad4-interacting Transcriptional Co-activator)

Cat no: D1496-50


Supplier: United States Biological
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Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:4000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: A431 and HeLa lysates Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D1496-50
Reactivities: Human, Mouse, Rat
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Decapping Enzyme hDcp1a, Putative Protein Product of Nbla00360, Transcription Factor SMIF
References: 1. Cougot, N., Babajko, S. and Seraphi, B., J. Cell Biol. 165: 31-40 (2004).
Additional info: Recognizes human DCP1A at ~75kD. A non-specific band is observed at 48kD in Western Blot. Species Crossreactivity: mouse and rat.

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