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DD2 (Q60) pAb

DD2 (Q60) pAb

Cat no: BS3804

Supplier: Bioworld Technology, Inc.
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DD1 is also designated AKR1C1, DDH or DDH1, while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3(alpha)-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), while DD4 also can be called AKR1C4, CD, CHDR or AKR1C6 (in rodents). DD1 and DD2 are 20(alpha)-HSDs, whereas DD3 and DD4 are the 3(alpha)- HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20(alpha)- HSD catalyzes the reaction of Progesterone to the inactive form 20(alpha)-hydroxyprogesterone.
Catalogue number: BS3804
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P52895
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 50-100 of Human DD2.
Species: DD2 (Q60) pAb detects endogenous levels of DD2 protein.
Molecular weight: ~ 37 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; 3-(alpha)-HSD3; 3(alpha)-HSD3; HSD3-3(alpha); HSD3-(alpha)3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase; AKR1C2; DDH2
Additional info: For research use only, not for use in diagnostic procedure.

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