Home  >  Products  >  DDAH2 (N(G),N(G)-dimethylarginine Dimethylaminohydrolase 2, DDAH-2, Dimethylarginine Dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase Protein, DDAH, G6A, NG30)

DDAH2 (N(G),N(G)-dimethylarginine Dimethylaminohydrolase 2, DDAH-2, Dimethylarginine Dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase Protein, DDAH, G6A, NG30)

Cat no: D1560-01C


Supplier: United States Biological
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DDAH2 plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Overexpression of DDAH2 has also been linked to increased VEGF mRNA expression and enhanced tube formation by cells grown in a 3-dimensional medium. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Mouse Heart extracts, Human Heart extract Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D1560-01C
Reactivities: Human, Mouse
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Leiper JM, Santa Maria J, Chubb A, MacAllister RJ, Charles IG, Whitley GS, Vallance P. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Biochem J 1999 Oct 1;343 Pt 1:209-14 PMID: 10493931.
Additional info: Recognizes DDAH2. Species Crossreactivity: human and mouse. Species sequence homology: rat.

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