DEFB121 pAb

Cat no: BS6249

Supplier: Bioworld Technology, Inc.

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(beta)-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, (beta)-defensins are developmentally regulated. The family of (beta)-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many (beta)-defensins also are involved in sperm maturation and capacitation. (beta)-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, (beta)-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other (beta)-defensins, it does not appear to be regulated by androgens.

Catalogue number:	BS6249
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q5J5C9
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human DEFB121.
Species:	DEFB121 pAb detects endogenous levels of DEFB1211 protein.
Molecular weight:	~ 8 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	beta 121; Beta-defensin 121; Beta-defensin 21; DB121; DEFB-21; DEFB121; Defensin; defensin; beta 121; defensin; beta 21; ESC42RELC;
Additional info:	For research use only, not for use in diagnostic procedure.

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DEFB121 pAb

Cat no: BS6249

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