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Defensin (alpha)1 (S52) pAb

Defensin (alpha)1 (S52) pAb

Cat no: BS3505

Supplier: Bioworld Technology, Inc.
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Defensins are a family of microbicidal and cytotoxic peptides which are made by neutrophils and are thought to be involved in host defense. Defensins are abundant in the granules of neutrophils and are also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract and vagina. There are six (alpha)-defensins, which are known as human neutrophil peptides (HNPs) in humans. HNP-1,2,3 and 4 are found in the microbicidal granules of neutrophils; HNP-5 and HNP-6 are located in Paneth cells of the intestinal tract. HNP-1 is found in the microbicidal granules of neutrophils and probably plays a role in phagocyte-mediated host defense. HNP-1, HNP-2 and HNP-3, which comprise about 30% of the total granule protein of the neutrophil, are secreted by most normal individuals. The HNP-1 protein is encoded by the a1-defensin (DEFA1) gene. HNP-3 is encoded by the a3-defensin (DEFA3) gene.
Catalogue number: BS3505
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P59665
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 30-70 of Human Defensin (alpha)1.
Species: Defensin (alpha)1 (S52) pAb detects endogenous levels of Defensin (alpha)1 protein.
Molecular weight: ~ 10 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Neutrophil defensin 1; Defensin, alpha 1; HNP-1; HNP1; HP-1; HP1; HP 1-56; Neutrophil defensin 2; HNP-2; HNP2; HP-2; HP2; DEFA1; DEF1; DEFA2; MRS; DEFA1B
Additional info: For research use only, not for use in diagnostic procedure.

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