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DGK-0 (S725) Peptide

DGK-0 (S725) Peptide

Cat no: BS2479P

Supplier: Bioworld Technology, Inc.
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Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-0 is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-0 co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-0 is the isoform responsive to alpha-Thrombin stimulation.
Catalogue number: BS2479P
Applications: Block/Neutralize/Inhibit
Swiss prot: P52824
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide DGK-0 (S725). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DGKQ; DAGK4; Diacylglycerol kinase theta; DGK-theta
Additional info: This peptide can be used with studies using BS2479 DGK-0 (S725) pAb.

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