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DGK-(delta) (S66) pAb

DGK-(delta) (S66) pAb

Cat no: BS2078

Supplier: Bioworld Technology, Inc.
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Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-(alpha) influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-(beta) is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-(gamma) encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-(delta) is most abundant in skeletal muscle. DGK-E shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-0 is most abundant in the cerebellum and hippocampus. DGK-l is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-n is closely related to DGK-(delta). DGK-(zeta)is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes.
Catalogue number: BS2078
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q16760
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 34-88 of Human DGK-(delta).
Species: DGK-(delta) (S66) pAb detects endogenous levels of DGK-(delta) protein.
Molecular weight: ~ 135 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Diacylglycerol kinase delta; DAG kinase delta; 130 kDa diacylglycerol kinase; Diglyceride kinase delta; DGK-delta; DGKD; KIAA0145; DGK(delta); DGK (delta)
Additional info: For research use only, not for use in diagnostic procedure.

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