DGK-E (S194) Peptide

Cat no: BS2281P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-alpha (80 kDa), -beta (90 kDa), and -gamma (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK-delta (130 kDa) and DGK-i (130 kDa) contain N-terminal pleckstrin homology (PH) domains and are classified as type II. Human DGK-E (64 kDa) contains no identifiable regulatory domains and is classified as a type III DGK. Human DGK-? (104 kDa) and -iota (130 kDa) possess C-terminal ankyrin repeats and are classified as type IV DGKs. Human DGK-0 (110 kDa) contains 3 cysteine-rich domains and a PH domain and is classified as a type V DGK.

Catalogue number:	BS2281P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P52429
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide DGK-E (S194). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Diacylglycerol kinase epsilon; DAG kinase epsilon; Diglyceride kinase epsilon; DGK-epsilon; DGKE; DAGK5
Additional info:	This peptide can be used with studies using BS2281 DGK-E (S194) pAb.

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DGK-E (S194) Peptide

Cat no: BS2281P

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