DHRS2 Peptide

Cat no: BS5698P

Supplier: Bioworld Technology, Inc.

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Additional Information

DHRS2 (dehydrogenase/reductase (SDR family) member 2), also known as SDR25C1 or HEP27, is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Catalogue number:	BS5698P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q13268
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide DHRS2. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Dehydrogenase/reductase SDR family member 2, mitochondrial; Dicarbonyl reductase HEP27; Protein D
Additional info:	This peptide can be used with studies using BS5698 DHRS2 pAb.

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DHRS2 Peptide

Cat no: BS5698P

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