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DHS (L87) Peptide

DHS (L87) Peptide

Cat no: BS3847P


Supplier: Bioworld Technology, Inc.
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Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.
Catalogue number: BS3847P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49366
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide DHS (L87). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Deoxyhypusine synthase; DHPS; DS
Additional info: This peptide can be used with studies using BS3847 DHS (L87) pAb.

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