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Di-(tert-Butyl-dimethylsilyl) Curcumin

Di-(tert-Butyl-dimethylsilyl) Curcumin

Cat no: 009092

Supplier: United States Biological
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Protected Curcumin. A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IkB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Form: Yellow Solid Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Catalogue number: 009092
Size: 25mg
Form: Yellow Solid
Alternative names: (1E,4Z,6E)-1,7-Bis[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
References: Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817

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