Home  >  Products  >  Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1, Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal dominant 1)
Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1, Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal dominant 1)

Diaphanous 1 (hDia1, DIAPH1, p140DIA, DFNA1, LFHL1, diaphanous homolog 1, DRF1, Diaphanous-related formin 1, LFHL1, low frequency hearing loss 1, deafness, autosomal dominant 1)

Cat no: D3470-01A

Supplier: United States Biological
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Diaphanous 1 is a member of the Formin homology (FH) family of cytoskeletal organizer proteins. It is required for cytokinesis and transcriptional activation of the serum response factor. It has also been suggested to contribute to localized actin polymerization and stress fiber formation, both by recruiting profiling to sites of Rho action and by cooperating with ROCK. The human Diaphanous 1 gene is associated with Premature Ovarian Failure (POF) and Nonsyndromic Deafness (DFNA1), an autosomal dominant, fully penetrant progressive hearing loss. Positive Control: 293T cell extracts Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D3470-01A
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: As reported
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Species Crossreactivity: Human. Other species have not been tested. Reactivity with mouse Dia1 is likely owing to complete identity between peptide used for this antibody production and mouse ortholog.

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