The stilbene derivatives diethylstilbestrol (DES), dienestrol and hexestrol are synthetic oestrogens that have been demonstrated to be genotoxic and carcinogenic in both animals and humans. DES has been used commercially as a growth-promoting agent in livestock, as a human medication to help maintain pregnancy and in the treatment of prostate cancer in humans, but was removed from these uses due to human carcinogenicity issues. DES, dienestrol and hexestrol are excreted in urine primarily as glucuronide tracer.
Applications:
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:
ELISA: 0.078ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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