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Dio-1 (S186) Peptide

Dio-1 (S186) Peptide

Cat no: BS2533P

Supplier: Bioworld Technology, Inc.
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Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.
Catalogue number: BS2533P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9BTC0
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Dio-1 (S186). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DIDO1; BYE1; C20ORF158; DATF-1; DATF1; DIDO2; DIDO3; DIO-1; DIO1; DJ885L7.8; DKFZP434P1115; FLJ11265; HDIDO1; KIAA0333; MGC16140
Additional info: This peptide can be used with studies using BS2533 Dio-1 (S186) pAb.

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