Home  >  Products  >  Dipeptidyl Peptidase 10 (Dipeptidyl-peptidase 10, DPP10, Dipeptidyl Peptidase X, Dipeptidyl Peptidase-like Protein 2, DPL2, DPPY, Dipeptidyl Peptidase IV Related Protein 3, DPRP-3, DPRP3)

Dipeptidyl Peptidase 10 (Dipeptidyl-peptidase 10, DPP10, Dipeptidyl Peptidase X, Dipeptidyl Peptidase-like Protein 2, DPL2, DPPY, Dipeptidyl Peptidase IV Related Protein 3, DPRP-3, DPRP3)

Cat no: D8065-32K


Supplier: United States Biological
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A novel gene, DPP10, also known as dipeptidylpeptidase 10, dipeptidyl peptidase related protein 3, dipeptidyl peptidase x, dpp10, and dprp3, Dipeptidyl peptidase-like protein 2, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Bone Marrow lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D8065-32K
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Malerba G, Pignatti PF. A review of asthma genetics: gene expression studies and recent candidates. J Appl Genet. 2005;46(1):93-104. Review.
Additional info: Recognizes human DPP10. Species sequence homology: canine.

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