Diphtheria Toxin, A Subunit (Corynebacterium diphtheriae Toxoid A, DT)

Cat no: D8065-43D

Supplier: United States Biological

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Description
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DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kD, it is then processed to form A and B fragments both of which appear to be required for toxicity. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	D8065-43D
Hosts:	Mouse
Applications:	ELISA
Size:	100ug
Form:	Supplied as a liquid in PBS, 0.09% sodium azide, 1% BSA.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein A affinity chromatography.
Additional info:	Recognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. Specific for both the free and bound A subunit of diphtheria toxin.

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Diphtheria Toxin, A Subunit (Corynebacterium diphtheriae Toxoid A, DT)

Cat no: D8065-43D

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